Anti-ARSI antibody (311-360 aa) (STJ91717)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ARSI at the amino acid range 311-360
General Information
| Short Description | Rabbit polyclonal anti-Arylsulfatase I (311-360 aa) for use in WB, IHC, IF and ELISA in Human and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Monkey |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ARSI |
| Gene ID | 340075 |
| Uniprot ID | ARSI_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ARSI at the amino acid range 311-360 |
| Immunogen Region | 311-360 aa |
| Specificity | Arylsulfatase I Polyclonal Antibody detects endogenous levels of Arylsulfatase I protein. |
Additional Info
| Post Translational Modifications | The oxidation of Cys-93 residue to 3-oxoalanine (also known as C(alpha)-formylglycine) by SUMF1/Sulfatase-modifying factor 1, seems critical for catalytic activity. |
| Function | Displays arylsulfatase activity at neutral pH, when co-expressed with SUMF1.arylsulfatase activity is measured in the secretion medium of retinal cell line, but no activity is recorded when measured in cell extracts. Lacks arylsulfatase activity. |
| Protein Name | Arylsulfatase IAsi |
| Database Links | Reactome: R-HSA-1663150Reactome: R-HSA-9840310 |
| Cellular Localisation | SecretedEndoplasmic ReticulumLocalized In The Intracellular Granular Structures |
| Alternative Antibody Names | Anti-Arylsulfatase I antibodyAnti-Asi antibodyAnti-ARSI antibody |
Information sourced from Uniprot.org