Anti-ARMT1 antibody (279-329 aa) (STJ195533)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human CF211 at the amino acid range 279-329
STJ195533
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General Information

Short DescriptionRabbit polyclonal anti-Damage-control phosphatase ARMT1 (279-329 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolARMT1
Gene ID79624
Uniprot IDARMT1_HUMAN
ImmunogenSynthesized peptide derived from the human CF211 at the amino acid range 279-329
Immunogen Region279-329 aa
SpecificityThis antibody detects endogenous levels of CF211 at Human/Mouse/Rat

Additional Info

Function Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.
Protein Name Damage-Control Phosphatase Armt1
Acidic Residue Methyltransferase 1
Protein-Glutamate O-Methyltransferase
Sugar Phosphate Phosphatase Armt1
Database Links
Cellular Localisation
Alternative Antibody Names Anti-Damage-Control Phosphatase Armt1 antibody
Anti-Acidic Residue Methyltransferase 1 antibody
Anti-Protein-Glutamate O-Methyltransferase antibody
Anti-Sugar Phosphate Phosphatase Armt1 antibody
Anti-ARMT1 antibody
Anti-C6orf211 antibody

Information sourced from Uniprot.org

Citations

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