| Short Description : | Rabbit polyclonal anti-Damage-control phosphatase ARMT1 (279-329 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARMT1 |
| Gene ID: | 79624 |
| Uniprot ID: | ARMT1_HUMAN |
| Immunogen: | Synthesized peptide derived from the human CF211 at the amino acid range 279-329 |
| Immunogen Region: | 279-329 aa |
| Specificity: | This antibody detects endogenous levels of CF211 at Human/Mouse/Rat |
| Function | Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response. |
| Protein Name | Damage-Control Phosphatase Armt1Acidic Residue Methyltransferase 1Protein-Glutamate O-MethyltransferaseSugar Phosphate Phosphatase Armt1 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Damage-Control Phosphatase Armt1 antibodyAnti-Acidic Residue Methyltransferase 1 antibodyAnti-Protein-Glutamate O-Methyltransferase antibodyAnti-Sugar Phosphate Phosphatase Armt1 antibodyAnti-ARMT1 antibodyAnti-C6orf211 antibody |
Information sourced from Uniprot.org
