Anti-ARMC9 antibody (713-763 aa) (STJ195936)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ARMC9 at the amino acid range 713-763
STJ195936
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General Information

Short DescriptionRabbit polyclonal anti-LisH domain-containing protein ARMC9 (713-763 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolARMC9
Gene ID80210
Uniprot IDARMC9_HUMAN
ImmunogenSynthesized peptide derived from the human ARMC9 at the amino acid range 713-763
Immunogen Region713-763 aa
SpecificityThis antibody detects endogenous levels of ARMC9 at Human/Mouse/Rat

Additional Info

Function Involved in ciliogenesis. It is required for appropriate acetylation and polyglutamylation of ciliary microtubules, and regulation of cilium length. Acts as a positive regulator of hedgehog (Hh)signaling. May participate in the trafficking and/or retention of GLI2 and GLI3 proteins at the ciliary tip.
Protein Name Lish Domain-Containing Protein Armc9
Armadillo Repeat-Containing Protein 9
Melanoma/Melanocyte-Specific Tumor Antigen Ku-Mel-1
Ns21
Database Links
Cellular Localisation Cytoplasm
Cytoskeleton
Cilium Basal Body
Cell Projection
Cilium
Microtubule Organizing Center
Centrosome
Centriole
Localized To The Proximal Region In Cilia
Stimulation Of Hh Signaling Leads To Redistribution Of Armc9 Toward The Ciliary Tip Within 6 Hours
Follow By A Gradual Return To Its Original Proximal Location
Localizes To The Daughter Centriole Of The Primary Cilium In Rpe1 Cells
Alternative Antibody Names Anti-Lish Domain-Containing Protein Armc9 antibody
Anti-Armadillo Repeat-Containing Protein 9 antibody
Anti-Melanoma/Melanocyte-Specific Tumor Antigen Ku-Mel-1 antibody
Anti-Ns21 antibody
Anti-ARMC9 antibody
Anti-KIAA1868 antibody

Information sourced from Uniprot.org

Citations

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