Anti-ARHGEF12 antibody (449-498 aa) (STJ93900)

SKU:
STJ93900
£48.00 - £252.00
Processing The item has been added

Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Rho guanine nucleotide exchange factor 12 (449-498 aa) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ARHGEF12
Gene ID: 23365
Uniprot ID: ARHGC_HUMAN
Immunogen Region: 449-498 aa
Specificity: LARG Polyclonal Antibody detects endogenous levels of LARG protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ARHGEF12 at the amino acid range 449-498
Function May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.
Protein Name Rho Guanine Nucleotide Exchange Factor 12
Leukemia-Associated Rhogef
Database Links Reactome: R-HSA-193648
Reactome: R-HSA-416482
Reactome: R-HSA-416572
Reactome: R-HSA-8980692
Reactome: R-HSA-9013026
Reactome: R-HSA-9013106
Reactome: R-HSA-9013148
Cellular Localisation Cytoplasm
Membrane
Translocated To The Membrane Upon Stimulation
Alternative Antibody Names Anti-Rho Guanine Nucleotide Exchange Factor 12 antibody
Anti-Leukemia-Associated Rhogef antibody
Anti-ARHGEF12 antibody
Anti-KIAA0382 antibody
Anti-LARG antibody

Information sourced from Uniprot.org