| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARHGEF10L |
| Gene ID: | 55160 |
| Uniprot ID: | ARGAL_HUMAN |
| Immunogen Region: | 1120-1230 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1120-1230 of human ARHGEF10L (NP_001011722). |
| Immunogen Sequence: | SHVGRELTRKKGILLQYRLR STAHLPGPLLSMREPAPADG AALEHSEEDGSIYEMADDPD IWVRSRPCARDAHRKEICSV AIISGGQGYRNFGSALGSSG RQAPCGETDST |
| Tissue Specificity | Detected in heart, liver, skeletal muscle, kidney and pancreas. |
| Function | Acts as a guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC. |
| Protein Name | Rho Guanine Nucleotide Exchange Factor 10-Like ProteinGrinchgef |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Rho Guanine Nucleotide Exchange Factor 10-Like Protein antibodyAnti-Grinchgef antibodyAnti-ARHGEF10L antibodyAnti-GRINCHGEF antibodyAnti-KIAA1626 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and CLUH knockout (KO) 293T cells, using [KO Validated] CLUH Rabbit polyclonal antibody (STJ11100855) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89789/358260/STJ11100855_1__37263.1713122599.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CLUH knockout (KO) 293T cells, using [KO Validated] CLUH Rabbit polyclonal antibody (STJ11100855) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
