Anti-ARFGAP2 antibody (242-521) (STJ119821)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ARFGAP2 (242-521) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ARFGAP2 |
| Gene ID | 84364 |
| Uniprot ID | ARFG2_HUMAN |
| Immunogen Region | 242-521 |
| Immunogen Sequence | SEIERQAQVAEKLREQQAAD AKKQAEESMVASMRLAYQEL QIDRKKEEKKLQNLEGKKRE QAERLGMGLVSRSSVSHSVL SEMQVIEQETPVSAKSSRSQ LDLFDDVGTFASGPPKYKDN PFSLGESFGSRWDTDAAWGM DRVEEKEPEVTISSIRPISE RATNRREVESRSSGLESSEA RQKFAGAKAISSDMFFGREV DAEYEARSRLQQLSGSSAIS SSDLFGDMDGAHGAGSVSL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 242-521 of human ARFGAP2 (NP_115765.2). |
Additional Info
| Function | GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. |
| Protein Name | Adp-Ribosylation Factor Gtpase-Activating Protein 2Arf Gap 2Gtpase-Activating Protein Znf289Zinc Finger Protein 289 |
| Database Links | Reactome: R-HSA-6807878Reactome: R-HSA-6811434Reactome: R-HSA-9013148 |
| Cellular Localisation | CytoplasmGolgi Apparatus MembranePeripheral Membrane ProteinCytoplasmic SideAlso Found On Peripheral Punctate Structures Likely To Be Endoplasmic Reticulum-Golgi Intermediate Compartment |
| Alternative Antibody Names | Anti-Adp-Ribosylation Factor Gtpase-Activating Protein 2 antibodyAnti-Arf Gap 2 antibodyAnti-Gtpase-Activating Protein Znf289 antibodyAnti-Zinc Finger Protein 289 antibodyAnti-ARFGAP2 antibodyAnti-ZNF289 antibodyAnti-Nbla10535 antibody |
Information sourced from Uniprot.org