| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARFGAP2 |
| Gene ID: | 84364 |
| Uniprot ID: | ARFG2_HUMAN |
| Immunogen Region: | 242-521 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 242-521 of human ARFGAP2 (NP_115765.2). |
| Immunogen Sequence: | SEIERQAQVAEKLREQQAAD AKKQAEESMVASMRLAYQEL QIDRKKEEKKLQNLEGKKRE QAERLGMGLVSRSSVSHSVL SEMQVIEQETPVSAKSSRSQ LDLFDDVGTFASGPPKYKDN PFSLGESFGSRWDTDAAWGM DRVEEKEPEVTISSIRPISE RATNRREVESRSSGLESSEA RQKFAGAKAISSDMFFGREV DAEYEARSRLQQLSGSSAIS SSDLFGDMDGAHGAGSVSL |
| Function | GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. |
| Protein Name | Adp-Ribosylation Factor Gtpase-Activating Protein 2Arf Gap 2Gtpase-Activating Protein Znf289Zinc Finger Protein 289 |
| Database Links | Reactome: R-HSA-6807878Reactome: R-HSA-6811434Reactome: R-HSA-9013148 |
| Cellular Localisation | CytoplasmGolgi Apparatus MembranePeripheral Membrane ProteinCytoplasmic SideAlso Found On Peripheral Punctate Structures Likely To Be Endoplasmic Reticulum-Golgi Intermediate Compartment |
| Alternative Antibody Names | Anti-Adp-Ribosylation Factor Gtpase-Activating Protein 2 antibodyAnti-Arf Gap 2 antibodyAnti-Gtpase-Activating Protein Znf289 antibodyAnti-Zinc Finger Protein 289 antibodyAnti-ARFGAP2 antibodyAnti-ZNF289 antibodyAnti-Nbla10535 antibody |
Information sourced from Uniprot.org