Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (794-844 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ARAP1 |
Gene ID: | 116985 |
Uniprot ID: | ARAP1_HUMAN |
Immunogen Region: | 794-844 aa |
Specificity: | ARAP1 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from part of the human protein at the amino acid range 794-844 |
Function | Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5. |
Protein Name | Arf-Gap With Rho-Gap Domain - Ank Repeat And Ph Domain-Containing Protein 1Centaurin-Delta-2Cnt-D2 |
Database Links | Reactome: R-HSA-8849469Reactome: R-HSA-8980692Reactome: R-HSA-9013148Reactome: R-HSA-9013149 |
Cellular Localisation | CytoplasmGolgi ApparatusGolgi Stack MembranePeripheral Membrane ProteinCell MembraneAssociated With Golgi Stacks In Resting CellsThroughout The Cytoplasm And In Surface Protrusion In Cells That Are In The Process Of Attaching To A Surface And Spreading |
Alternative Antibody Names | Anti-Arf-Gap With Rho-Gap Domain - Ank Repeat And Ph Domain-Containing Protein 1 antibodyAnti-Centaurin-Delta-2 antibodyAnti-Cnt-D2 antibodyAnti-ARAP1 antibodyAnti-CENTD2 antibodyAnti-KIAA0782 antibody |
Information sourced from Uniprot.org