Anti-Appetite-regulating hormone antibody (C-Term) (STJA0040667)

SKU:
STJA0040667-200
£638.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Chicken
Applications: ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Chicken polyclonal anti-Appetite-regulating hormone (C-Term) for use in ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgY
Formulation: PBS with 0.02% sodium azide.
Purification: Affinity-purified
Storage Instruction: Short term storage at 2-8°C for one week. At-20°C as an undiluted liquid for up to 12 months.
Gene Symbol: GHRL
Gene ID: 51738
Uniprot ID: GHRL_HUMAN
Immunogen Region: C-Term
Specificity: Antibody to Ghrelin (17-28) : Affinity purified.
Immunogen: Synthetic peptide from human Ghrelin, C-terminal, (17-28 aa)
Immunogen Sequence: Human
Tissue Specificity Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy.
Post Translational Modifications O-octanoylated by GOAT/MBOAT4. O-octanoylation or O-decanoylation is essential for ghrelin activity. The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28-C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. A small fraction of ghrelin, ghrelin-28-C10:1, may be modified with a singly unsaturated carboxylic acid. Also O-acetylated and O-butyrylated on Ser-26 to minor levels. Amidation of Leu-98 is essential for obestatin activity.
Function Ghrelin-27: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. Ghrelin-28: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. Obestatin: May be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility.
Protein Name Appetite-Regulating Hormone
Growth Hormone Secretagogue
Growth Hormone-Releasing Peptide
Motilin-Related Peptide
Protein M46 Cleaved Into - Ghrelin-27 - Ghrelin-28
Ghrelin - Obestatin
Database Links Reactome: R-HSA-375276 Q9UBU3-1
Reactome: R-HSA-416476 Q9UBU3-1
Reactome: R-HSA-422085
Cellular Localisation Secreted
Alternative Antibody Names Anti-Appetite-Regulating Hormone antibody
Anti-Growth Hormone Secretagogue antibody
Anti-Growth Hormone-Releasing Peptide antibody
Anti-Motilin-Related Peptide antibody
Anti-Protein M46 Cleaved Into - Ghrelin-27 - Ghrelin-28 antibody
Anti-Ghrelin - Obestatin antibody
Anti-GHRL antibody
Anti-MTLRP antibody
Anti-UNQ524 antibody
Anti-PRO1066 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJA0040673 Anti-Appetite-regulating hormone, active antibody (24-33 aa) (STJA0040673) Chicken Polyclonal Human/Mouse/Rat ELISA
STJE0003324 Human GHRL (Appetite-regulating hormone) Competitive ELISA Kit (STJE0003324) Human ELISA
STJE0004603 Mouse Ghrl (Appetite-regulating hormone) Competitive ELISA Kit (STJE0004603) Mouse ELISA
STJA0040928 Anti-Activity-regulated cytoskeleton-associated protein antibody (C-Term) (STJA0040928) Rabbit Polyclonal Human/Mouse/Rat IHC-F
STJA0041365 Anti-C-Raf antibody (C-Term) (STJA0041365) Rabbit Polyclonal Human/Mouse/Rat ELISA/WB

Related Products

!