Anti-APOBEC3A antibody (27-76 aa) (STJ91635)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human APOBEC3A at the amino acid range 27-76
General Information
| Short Description | Rabbit polyclonal anti-DNA dC->dU-editing enzyme APOBEC-3A (27-76 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | APOBEC3A |
| Gene ID | 100913187/200315 |
| Uniprot ID | ABC3A_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human APOBEC3A at the amino acid range 27-76 |
| Immunogen Region | 27-76 aa |
| Specificity | APOBEC3A Polyclonal Antibody detects endogenous levels of APOBEC3A protein. |
Additional Info
| Function | DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. |
| Protein Name | Dna Dc->Du-Editing Enzyme Apobec-3aA3aPhorbolin-1 |
| Database Links | Reactome: R-HSA-72200Reactome: R-HSA-75094 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Dna Dc->Du-Editing Enzyme Apobec-3a antibodyAnti-A3a antibodyAnti-Phorbolin-1 antibodyAnti-APOBEC3A antibody |
Information sourced from Uniprot.org