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Anti-APOB antibody (1890-2190 aa) (STJ11107041)

Anti-APOB antibody (1890-2190 aa) (STJ11107041)

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STJ11107041

£112.50 - £524.50

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General Information
Product Properties
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Additional Info
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Host:	Rabbit
Applications:	WB/IHC-P/IF/ICC/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification:	Affinity purification
Concentration:	Lot specific
Dilution Range:	WB:1:500-1:1000 IHC-P:1:50-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.

Gene Symbol:	APOB
Gene ID:	338
Uniprot ID:	APOB_HUMAN
Immunogen Region:	1890-2190 aa
Specificity:	Recombinant fusion protein containing a sequence corresponding to amino acids 1890-2190 of human APOB (NP_000375.3).
Immunogen Sequence:	LHFSNVFRSVMAPFTMTIDA HTNGNGKLALWGEHTGQLYS KFLLKAEPLAFTFSHDYKGS TSHHLVSRKSISAALEHKVS ALLTPAEQTGTWKLKTQFNN NEYSQDLDAYNTKDKIGVEL TGRTLADLTLLDSPIKVPLL LSEPINIIDALEMRDAVEKP QEFTIVAFVKYDKNQDVHSI NLPFFETLQEYFERNRQTII VVLENVQRNLKHINIDQFVR KYRAALGKLPQQANDYLNS

Post Translational Modifications	Palmitoylated.structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.
Function	Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
Protein Name	Apolipoprotein B-100 Apo B-100 Cleaved Into - Apolipoprotein B-48 Apo B-48
Database Links	Reactome: R-HSA-202733 Reactome: R-HSA-3000471 Reactome: R-HSA-3000480 Reactome: R-HSA-3000484 Reactome: R-HSA-3000497 Reactome: R-HSA-381426 Reactome: R-HSA-432142 Reactome: R-HSA-5686938 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 Reactome: R-HSA-8866423 Reactome: R-HSA-8957275 Reactome: R-HSA-8963888 Reactome: R-HSA-8963901 Reactome: R-HSA-8964026 Reactome: R-HSA-8964038 Reactome: R-HSA-8964041 Reactome: R-HSA-8964046 Reactome: R-HSA-9707616 Reactome: R-HSA-975634
Cellular Localisation	Cytoplasm Secreted Lipid Droplet
Alternative Antibody Names	Anti-Apolipoprotein B-100 antibody Anti-Apo B-100 Cleaved Into - Apolipoprotein B-48 antibody Anti-Apo B-48 antibody Anti-APOB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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