| Host: | Mouse |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Apolipoprotein A-I is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 5F4F5 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | APOA1 |
| Gene ID: | 335 |
| Uniprot ID: | APOA1_HUMAN |
| Specificity: | ApoA-I Monoclonal Antibody detects endogenous levels of ApoA-I protein. |
| Immunogen: | Purified recombinant fragment of human ApoA-I expressed in E. Coli. |
| Post Translational Modifications | Glycosylated. Palmitoylated. Phosphorylation sites are present in the extracellular medium. |
| Function | Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. |
| Protein Name | Apolipoprotein A-I Apo-Ai Apoa-I Apolipoprotein A1 Cleaved Into - Proapolipoprotein A-I Proapoa-I - Truncated Apolipoprotein A-I Apolipoprotein A-I(1-242 |
| Database Links | Reactome: R-HSA-114608 Reactome: R-HSA-1369062 Reactome: R-HSA-1989781 Reactome: R-HSA-2168880 Reactome: R-HSA-3000471 Reactome: R-HSA-3000480 Reactome: R-HSA-381426 Reactome: R-HSA-5682113 Reactome: R-HSA-8957275 Reactome: R-HSA-8963888 Reactome: R-HSA-8963896 Reactome: R-HSA-8963901 Reactome: R-HSA-8964011 Reactome: R-HSA-8964058 Reactome: R-HSA-9707616 Reactome: R-HSA-975634 Reactome: R-HSA-977225 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Apolipoprotein A-I antibody Anti-Apo-Ai antibody Anti-Apoa-I antibody Anti-Apolipoprotein A1 Cleaved Into - Proapolipoprotein A-I antibody Anti-Proapoa-I - Truncated Apolipoprotein A-I antibody Anti-Apolipoprotein A-I(1-242 antibody Anti-APOA1 antibody |
Information sourced from Uniprot.org