Anti-APIP antibody (133-183 aa) (STJ194510)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human MTNB at the amino acid range 133-183
General Information
| Short Description | Rabbit polyclonal anti-Methylthioribulose-1-phosphate dehydratase (133-183 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | APIP |
| Gene ID | 51074 |
| Uniprot ID | MTNB_HUMAN |
| Immunogen | Synthesized peptide derived from the human MTNB at the amino acid range 133-183 |
| Immunogen Region | 133-183 aa |
| Specificity | This antibody detects endogenous levels of MTNB at Human/Mouse |
Additional Info
| Function | Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death. |
| Protein Name | Methylthioribulose-1-Phosphate DehydrataseMtru-1-P DehydrataseApaf1-Interacting ProteinHapip |
| Database Links | Reactome: R-HSA-111458Reactome: R-HSA-1237112Reactome: R-HSA-9627069 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Methylthioribulose-1-Phosphate Dehydratase antibodyAnti-Mtru-1-P Dehydratase antibodyAnti-Apaf1-Interacting Protein antibodyAnti-Hapip antibodyAnti-APIP antibodyAnti-CGI-29 antibody |
Information sourced from Uniprot.org