Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Aminopeptidase N (881-930 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:100-1:300ELISA 1:10000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ANPEP |
Gene ID: |
290 |
Uniprot ID: |
AMPN_HUMAN |
Immunogen Region: |
881-930 aa |
Specificity: |
CD13 Polyclonal Antibody detects endogenous levels of CD13 protein. |
Immunogen: |
Synthesized peptide derived from Aminopeptidase N at the amino acid range 881-930 |
Post Translational Modifications | Sulfated. N- and O-glycosylated. May undergo proteolysis and give rise to a soluble form. |
Function | Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity. (Microbial infection) Acts as a receptor for human coronavirus 229E/HCoV-229E. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. (Microbial infection) Mediates as well Human cytomegalovirus (HCMV) infection. |
Protein Name | Aminopeptidase NAp-NHapnAlanyl AminopeptidaseAminopeptidase MAp-MMicrosomal AminopeptidaseMyeloid Plasma Membrane Glycoprotein Cd13Gp150Cd Antigen Cd13 |
Database Links | Reactome: R-HSA-2022377Reactome: R-HSA-6798695 |
Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinAlso Found As A Soluble Form |
Alternative Antibody Names | Anti-Aminopeptidase N antibodyAnti-Ap-N antibodyAnti-Hapn antibodyAnti-Alanyl Aminopeptidase antibodyAnti-Aminopeptidase M antibodyAnti-Ap-M antibodyAnti-Microsomal Aminopeptidase antibodyAnti-Myeloid Plasma Membrane Glycoprotein Cd13 antibodyAnti-Gp150 antibodyAnti-Cd Antigen Cd13 antibodyAnti-ANPEP antibodyAnti-APN antibodyAnti-CD13 antibodyAnti-PEPN antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance