| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Anoctamin-3 (518-568 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ANO3 |
| Gene ID: | 63982 |
| Uniprot ID: | ANO3_HUMAN |
| Immunogen Region: | 518-568 aa |
| Specificity: | This antibody detects endogenous levels of ANO3 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human ANO3 at the amino acid range 518-568 |
| Function | Has calcium-dependent phospholipid scramblase activity.scrambles phosphatidylcholine and galactosylceramide. Seems to act as potassium channel regulator and may inhibit pain signaling.can facilitate KCNT1/Slack channel activity by promoting its full single-channel conductance at very low sodium concentrations and by increasing its sodium sensitivity. Does not exhibit calcium-activated chloride channel (CaCC) activity. |
| Protein Name | Anoctamin-3 Transmembrane Protein 16c |
| Database Links | Reactome: R-HSA-2672351 Reactome: R-HSA-9733458 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Shows An Intracellular Localization |
| Alternative Antibody Names | Anti-Anoctamin-3 antibody Anti-Transmembrane Protein 16c antibody Anti-ANO3 antibody Anti-C11orf25 antibody Anti-TMEM16C antibody Anti-GENX-3947 antibody |
Information sourced from Uniprot.org