| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Anoctamin-3 (518-568 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ANO3 |
| Gene ID: |
63982 |
| Uniprot ID: |
ANO3_HUMAN |
| Immunogen Region: |
518-568 aa |
| Specificity: |
This antibody detects endogenous levels of ANO3 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human ANO3 at the amino acid range 518-568 |
| Function | Has calcium-dependent phospholipid scramblase activity.scrambles phosphatidylcholine and galactosylceramide. Seems to act as potassium channel regulator and may inhibit pain signaling.can facilitate KCNT1/Slack channel activity by promoting its full single-channel conductance at very low sodium concentrations and by increasing its sodium sensitivity. Does not exhibit calcium-activated chloride channel (CaCC) activity. |
| Protein Name | Anoctamin-3Transmembrane Protein 16c |
| Database Links | Reactome: R-HSA-2672351Reactome: R-HSA-9733458 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinShows An Intracellular Localization |
| Alternative Antibody Names | Anti-Anoctamin-3 antibodyAnti-Transmembrane Protein 16c antibodyAnti-ANO3 antibodyAnti-C11orf25 antibodyAnti-TMEM16C antibodyAnti-GENX-3947 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
