Immunohistochemical analysis of paraffin-embedded human spleen. 1, Antibody was diluted at 1:200 (4ยฐC overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-ANKRD11 antibody (557-607 aa) (STJ196173)

⇓ Datasheet ⇓ SDS
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ANR11 at the amino acid range 557-607
STJ196173
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General Information

Short DescriptionRabbit polyclonal anti-Ankyrin repeat domain-containing protein 11 (557-607 aa) for use in IHC and IF in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC/IF
HostRabbit
ReactivityHuman/Rat/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeIHC-P 1:50-200
IF 1:50-200
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolANKRD11
Gene ID29123
Uniprot IDANR11_HUMAN
ImmunogenSynthesized peptide derived from the human ANR11 at the amino acid range 557-607
Immunogen Region557-607 aa
SpecificityThis antibody detects endogenous levels of ANR11 at Human

Additional Info

Function Chromatin regulator which modulates histone acetylation and gene expression in neural precursor cells. May recruit histone deacetylases (HDACs) to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation. Has a role in proliferation and development of cortical neural precursors. May also regulate bone homeostasis.
Protein Name Ankyrin Repeat Domain-Containing Protein 11
Ankyrin Repeat-Containing Cofactor 1
Database Links
Cellular Localisation Nucleus
Localizes To Chromatin During Prometaphase
Alternative Antibody Names Anti-Ankyrin Repeat Domain-Containing Protein 11 antibody
Anti-Ankyrin Repeat-Containing Cofactor 1 antibody
Anti-ANKRD11 antibody
Anti-ANCO1 antibody

Information sourced from Uniprot.org

Citations

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