Anti-ANKRD1 antibody (1-130) [S4705RM] (STJ11104705)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Ankyrin Repeat Domain-Containing Protein 1 (1-130) antibody for use in WB and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4705RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ANKRD1 |
| Gene ID | 27063 |
| Uniprot ID | ANKR1_HUMAN |
| Immunogen Region | 1-130 |
| Immunogen Sequence | MMVLKVEELVTGKKNGNGEA GEFLPEDFRDGEYEAAVTLE KQEDLKTLLAHPVTLGEQQW KSEKQREAELKKKKLEQRSK LENLEDLEIIIQLKKRKKYR KTKVPVVKEPEPEIITEPVD VPTFLKAALE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human ANKRD1 (NP_055206.2). |
Additional Info
| Tissue Specificity | Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells. |
| Function | May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. |
| Protein Name | Ankyrin Repeat Domain-Containing Protein 1Cardiac Ankyrin Repeat ProteinCytokine-Inducible Gene C-193 ProteinCytokine-Inducible Nuclear Protein |
| Database Links | Reactome: R-HSA-1989781 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ankyrin Repeat Domain-Containing Protein 1 antibodyAnti-Cardiac Ankyrin Repeat Protein antibodyAnti-Cytokine-Inducible Gene C-193 Protein antibodyAnti-Cytokine-Inducible Nuclear Protein antibodyAnti-ANKRD1 antibodyAnti-C193 antibodyAnti-CARP antibodyAnti-HA1A2 antibody |
Information sourced from Uniprot.org