| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ANKHD1 |
| Gene ID: | 404734/54882 |
| Uniprot ID: | ANKH1_HUMAN |
| Immunogen Region: | 1620-1800 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1620-1800 of human ANKHD1 (NP_060217.1). |
| Immunogen Sequence: | VNSSKYPSLLLHSQEEKTST ATSKTQTRLEGEVTPNSLST SYKTVSLPLSSPNIKLNLTS PKRGQKREEGWKEVVRRSKK LSVPASVVSRIMGRGGCNIT AIQDVTGAHIDVDKQKDKNG ERMITIRGGTESTRYAVQLI NALIQDPAKELEDLIPKNHI RTPASTKSIHANFSSGVGTT A |
| Tissue Specificity | Ubiquitous with high expression in cervix, spleen and brain. Expressed in hematopoietic cells with increased expression in leukemia cells. Isoform 2 is highly expressed in spleen with almost no expression in muscle and brain. |
| Function | May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases. |
| Protein Name | Ankyrin Repeat And Kh Domain-Containing Protein 1Hiv-1 Vpr-Binding Ankyrin Repeat ProteinMultiple Ankyrin Repeats Single Kh DomainHmask |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ankyrin Repeat And Kh Domain-Containing Protein 1 antibodyAnti-Hiv-1 Vpr-Binding Ankyrin Repeat Protein antibodyAnti-Multiple Ankyrin Repeats Single Kh Domain antibodyAnti-Hmask antibodyAnti-ANKHD1 antibodyAnti-KIAA1085 antibodyAnti-MASK antibodyAnti-VBARP antibodyAnti-PP2500 antibody |
Information sourced from Uniprot.org