| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
ANGPTL7 |
| Gene ID: |
10218 |
| Uniprot ID: |
ANGL7_HUMAN |
| Immunogen Region: |
27-346 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 27-346 of human ANGPTL7 (NP_066969.1). |
| Immunogen Sequence: |
QKLSKHKTPAQPQLKAANCC EEVKELKAQVANLSSLLSEL NKKQERDWVSVVMQVMELES NSKRMESRLTDAESKYSEMN NQIDIMQLQAAQTVTQTSAD AIYDCSSLYQKNYRISGVYK LPPDDFLGSPELEVFCDMET SGGGWTIIQRRKSGLVSFYR DWKQYKQGFGSIRGDFWLGN EHIHRLSRQPTRLRVEMEDW EGNLRYAEYSHFVLGNELNS YRLFLGNYTGNVGNDALQY |
| Tissue Specificity | Highly expressed in the cornea (at protein level). Expression is restricted to the stromal layer. Also detected at the junction between the corneal stromal layer and the conjuctiva. Not detected in the sclera. |
| Function | Has a role in the formation and organization of the extracellular matrix. In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure. Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency. |
| Protein Name | Angiopoietin-Related Protein 7Angiopoietin-Like FactorAngiopoietin-Like Protein 7Cornea-Derived Transcript 6 Protein |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Angiopoietin-Related Protein 7 antibodyAnti-Angiopoietin-Like Factor antibodyAnti-Angiopoietin-Like Protein 7 antibodyAnti-Cornea-Derived Transcript 6 Protein antibodyAnti-ANGPTL7 antibodyAnti-CDT6 antibodyAnti-UNQ313 antibodyAnti-PRO356 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
