• Anti-AMACR p504s antibody [EPUM1] (STJ16101677)

Anti-AMACR p504s antibody [EPUM1] (STJ16101677)

SKU:
STJ16101677-1

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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Alpha-Methylacyl-CoA Racemase is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: EPUM1
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Tissue culture supernatant with 15mM sodium azide
Concentration: >=84 mg/L
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: Prokaryotic recombinant protein corresponding to 382 amino acids of the human alpha-methylacyl-CoA racemase molecule.
Background Alpha-methylacyl-CoA racemase (AMACR) , also known as p504s, is a mitochondrial and peroxisomal enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism, and is expressed in normal liver (hepatocytes) , kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). Expression is granular and cytoplasmic. AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.

Information sourced from Uniprot.org

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