| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AMACR |
| Gene ID: | 23600 |
| Uniprot ID: | AMACR_HUMAN |
| Immunogen Region: | 1-138 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-138 of human AMACR (NP_055139.4). |
| Immunogen Sequence: | MALQGISVVELSGLAPGPFC AMVLADFGARVVRVDRPGSR YDVSRLGRGKRSLVLDLKQP RGAAVLRRLCKRSDVLLEPF RRGVMEKLQLGPEILQRENP RLIYARLSGFGQSGSFCRLA GHDINYLALSGVLSKIGR |
| Function | Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2-(4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs. |
| Protein Name | Alpha-Methylacyl-Coa Racemase2-Methylacyl-Coa Racemase |
| Database Links | Reactome: R-HSA-193368Reactome: R-HSA-193775Reactome: R-HSA-389887Reactome: R-HSA-9033241 |
| Cellular Localisation | PeroxisomeMitochondrion |
| Alternative Antibody Names | Anti-Alpha-Methylacyl-Coa Racemase antibodyAnti-2-Methylacyl-Coa Racemase antibodyAnti-AMACR antibody |
Information sourced from Uniprot.org
