Anti-ALMS1 antibody (C-Term) (STJ70332)

Name: Anti-ALMS1 antibody (C-Term) (STJ70332)
SKU: STJ70332-100
Price: 312.5 GBP
Availability: InStock

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SPECIFICATIONS

ClonalityPolyclonal

HostGoat

ConjugationUnconjugated

IsotypeIgG

STJ70332-100

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Short Description	Goat polyclonal antibody anti-ALMS1 (C-Term) is suitable for use in ELISA and Immunofluorescence research applications.
Applications	Pep-ELISA/IF
Host	Goat
Reactivity	Human/Mouse/Rat/Dog/Cow
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	0.5 mg/mL
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution Range	Peptide ELISA: antibody detection limit dilution 1:4000. IF: Strong expression of the protein seen in the cytoplasm of HepG2 and HeLa cells. Recommended concentration: 10µg/ml.
Formulation	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage Instruction	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol	ALMS1
Gene ID	7840
Uniprot ID	ALMS1_HUMAN
Accession Number	NP_055935.4
Immunogen Region	C-Term
Immunogen Sequence	RVTNQLLGRKVPWD
Specificity	The C terminus of ALMS1 shares an 8 amino acid stretch with two other human proteins: hypothetical protein (XP_169104) and ERAL1 (NP_005693). However, this stretch is located internally in these two proteins and so will most likely not cross-react wi

Function	Involved in PCM1-dependent intracellular transport. Required, directly or indirectly, for the localization of NCAPD2 to the proximal ends of centrioles. Required for proper formation and/or maintenance of primary cilia (PC), microtubule-based structures that protrude from the surface of epithelial cells.
Protein Name	Centrosome-Associated Protein Alms1 Alstrom Syndrome Protein 1
Database Links	Reactome: R-HSA-2565942 Reactome: R-HSA-380259 Reactome: R-HSA-380270 Reactome: R-HSA-380284 Reactome: R-HSA-380320 Reactome: R-HSA-5620912 Reactome: R-HSA-8854518
Cellular Localisation	Cytoplasm Cytoskeleton Microtubule Organizing Center Centrosome Cilium Basal Body Spindle Pole Associated With Centrosomes And Basal Bodies At The Base Of Primary Cilia Specifically Locates To The Proximal Ends Of Centrioles And Basal Bodies Colocalizes Partially With Ncapd2 At These Sites During Mitosis Localizes To Both Spindle Poles
Alternative Antibody Names	Anti-Centrosome-Associated Protein Alms1 antibody Anti-Alstrom Syndrome Protein 1 antibody Anti-ALMS1 antibody Anti-KIAA0328 antibody

Information sourced from Uniprot.org