Anti-Aldo-keto reductase 7A3/AKR7A3 antibody (1-331aa) [AT2E11] (STJA0041618)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenRecombinant human AKR7A3 (1-331aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-Aldo-keto reductase 7A3/AKR7A3 (1-331aa) for use in ELISA and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT2E11 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-G affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AKR7A3 |
| Gene ID | 22977 |
| Uniprot ID | ARK73_HUMAN |
| Accession Number | AAH25709 |
| Immunogen | Recombinant human AKR7A3 (1-331aa) purified from E. coli |
| Immunogen Region | 1-331aa |
Additional Info
| Tissue Specificity | Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium. |
| Function | Catalyzes the NADPH-dependent reduction of various carbonyl-containing compounds, including aldehydes, ketones, and toxic products from cellular metabolism or environmental exposure. Can reduce the dialdehyde form of aflatoxin B1 (AFB1) into alcohol derivatives, via monoaldehydes intermediates. Can reduce the dialdehyde form of aflatoxin B1 (AFB1) into alcohol derivatives, via monoaldehydes intermediates, thus preventing the formation of protein adducts that contribute to AFB1-induced toxicity. |
| Protein Name | Aldo-Keto Reductase Family 7 Member A3Afb1 Aldehyde Reductase 2Afb1-Ar 2Aflatoxin B1 Aldehyde Reductase Member 3 |
| Database Links | Reactome: R-HSA-5423646 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Aldo-Keto Reductase Family 7 Member A3 antibodyAnti-Afb1 Aldehyde Reductase 2 antibodyAnti-Afb1-Ar 2 antibodyAnti-Aflatoxin B1 Aldehyde Reductase Member 3 antibodyAnti-AKR7A3 antibodyAnti-AFAR2 antibody |
Information sourced from Uniprot.org