Anti-ALDH3B1 antibody (51-100 aa) (STJ91555)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ALDH3B1 at the amino acid range 51-100
General Information
| Short Description | Rabbit polyclonal anti-Aldehyde dehydrogenase family 3 member B1 (51-100 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ALDH3B1 |
| Gene ID | 221 |
| Uniprot ID | AL3B1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ALDH3B1 at the amino acid range 51-100 |
| Immunogen Region | 51-100 aa |
| Specificity | ALDH3B1 Polyclonal Antibody detects endogenous levels of ALDH3B1 protein. |
Additional Info
| Post Translational Modifications | Dually lipidated in the C-terminus.prenylation occurs prior to, and is a prerequisite for palmitoylation. It is also required for activity towards long-chain substrates. |
| Function | Oxidizes medium and long chain saturated and unsaturated fatty aldehydes generated in the plasma membrane into non-toxic fatty acids. May have a protective role against the cytotoxicity induced by lipid peroxidation. Short-chain fatty aldehydes are not good substrates. Can use both NADP(+) and NAD(+) as electron acceptor in vitro, however in vivo preference will depend on their tissue levels. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. Able to metabolize aromatic aldehydes such as benzaldehyde to their acid form. |
| Protein Name | Aldehyde Dehydrogenase Family 3 Member B1 Aldehyde Dehydrogenase 7Long-Chain Fatty Aldehyde DehydrogenaseMedium-Chain Fatty Aldehyde Dehydrogenase |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-9845614 |
| Cellular Localisation | Cell MembraneLipid-AnchorPrimarily In The Plasma Membrane As Well As In Some Punctate Structures In The Cytoplasm |
| Alternative Antibody Names | Anti-Aldehyde Dehydrogenase Family 3 Member B1 antibodyAnti-Aldehyde Dehydrogenase 7 antibodyAnti-Long-Chain Fatty Aldehyde Dehydrogenase antibodyAnti-Medium-Chain Fatty Aldehyde Dehydrogenase antibodyAnti-ALDH3B1 antibodyAnti-ALDH7 antibody |
Information sourced from Uniprot.org