| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Aldehyde dehydrogenase family 3 member B1 (51-100 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:40000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ALDH3B1 |
| Gene ID: | 221 |
| Uniprot ID: | AL3B1_HUMAN |
| Immunogen Region: | 51-100 aa |
| Specificity: | ALDH3B1 Polyclonal Antibody detects endogenous levels of ALDH3B1 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ALDH3B1 at the amino acid range 51-100 |
| Post Translational Modifications | Dually lipidated in the C-terminus.prenylation occurs prior to, and is a prerequisite for palmitoylation. It is also required for activity towards long-chain substrates. |
| Function | Oxidizes medium and long chain saturated and unsaturated fatty aldehydes generated in the plasma membrane into non-toxic fatty acids. May have a protective role against the cytotoxicity induced by lipid peroxidation. Short-chain fatty aldehydes are not good substrates. Can use both NADP(+) and NAD(+) as electron acceptor in vitro, however in vivo preference will depend on their tissue levels. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. Able to metabolize aromatic aldehydes such as benzaldehyde to their acid form. |
| Protein Name | Aldehyde Dehydrogenase Family 3 Member B1 Aldehyde Dehydrogenase 7 Long-Chain Fatty Aldehyde Dehydrogenase Medium-Chain Fatty Aldehyde Dehydrogenase |
| Database Links | Reactome: R-HSA-6798695 Reactome: R-HSA-9845614 |
| Cellular Localisation | Cell Membrane Lipid-Anchor Primarily In The Plasma Membrane As Well As In Some Punctate Structures In The Cytoplasm |
| Alternative Antibody Names | Anti-Aldehyde Dehydrogenase Family 3 Member B1 antibody Anti-Aldehyde Dehydrogenase 7 antibody Anti-Long-Chain Fatty Aldehyde Dehydrogenase antibody Anti-Medium-Chain Fatty Aldehyde Dehydrogenase antibody Anti-ALDH3B1 antibody Anti-ALDH7 antibody |
Information sourced from Uniprot.org