| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ALDH3A1 |
| Gene ID: | 218 |
| Uniprot ID: | AL3A1_HUMAN |
| Immunogen Region: | 1-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ALDH3A1 (NP_001128640.1). |
| Immunogen Sequence: | MSKISEAVKRARAAFSSGRT RPLQFRIQQLEALQRLIQEQ EQELVGALAADLHKNEWNAY YEEVVYVLEEIEYMIQKLPE WAADEPVEKTPQTQQDELYI HSEPLGVVLVIGTWNYPFNL TIQPMVGAIAAGNSVVLKPS ELSENMASLLATIIPQYLDK DLYPVINGGVPETTELLKER FDHILYTGSTGVGKIIMTAA AKHLTPVTLELGGKSPCYVD KNCDLDVACRRIAWGKFMN |
| Tissue Specificity | High levels in stomach, esophagus and lung.low level in the liver and kidney. |
| Function | ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids. Preferentially oxidizes aromatic aldehyde substrates. Comprises about 50 percent of corneal epithelial soluble proteins. May play a role in preventing corneal damage caused by ultraviolet light. |
| Protein Name | Aldehyde Dehydrogenase - Dimeric Nadp-PreferringAldhiiiAldehyde Dehydrogenase 3Aldehyde Dehydrogenase Family 3 Member A1 |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Aldehyde Dehydrogenase - Dimeric Nadp-Preferring antibodyAnti-Aldhiii antibodyAnti-Aldehyde Dehydrogenase 3 antibodyAnti-Aldehyde Dehydrogenase Family 3 Member A1 antibodyAnti-ALDH3A1 antibodyAnti-ALDH3 antibody |
Information sourced from Uniprot.org
