Anti-ALDH1A2 antibody (1-100) [S6MR] (STJ11102426)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal ALDH1A2 (1-100) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S6MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ALDH1A2 |
| Gene ID | 8854 |
| Uniprot ID | AL1A2_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MTSSKIEMPGEVKADPAALM ASLHLLPSPTPNLEIKYTKI FINNEWQNSESGRVFPVYNP ATGEQVCEVQEADKADIDKA VQAARLAFSLGSVWRRMDAS |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ALDH1A2 (NP_003879.2). |
Additional Info
| Function | Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively. Retinoate signaling is critical for the transcriptional control of many genes, for instance it is crucial for initiation of meiosis in both male and female (Probable). Recognizes retinal as substrate, both in its free form and when bound to cellular retinol-binding protein. Can metabolize octanal and decanal, but has only very low activity with benzaldehyde, acetaldehyde and propanal. Displays complete lack of activity with citral. |
| Protein Name | Retinal Dehydrogenase 2Raldh 2Raldh2Aldehyde Dehydrogenase Family 1 Member A2Aldh1a2Retinaldehyde-Specific Dehydrogenase Type 2Raldh(Ii |
| Database Links | Reactome: R-HSA-5365859 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Retinal Dehydrogenase 2 antibodyAnti-Raldh 2 antibodyAnti-Raldh2 antibodyAnti-Aldehyde Dehydrogenase Family 1 Member A2 antibodyAnti-Aldh1a2 antibodyAnti-Retinaldehyde-Specific Dehydrogenase Type 2 antibodyAnti-Raldh(Ii antibodyAnti-ALDH1A2 antibodyAnti-RALDH2 antibody |
Information sourced from Uniprot.org