| Host: |
Rabbit |
| Applications: |
WB/IHC-P/IF/ICC/IP/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:100IP:0.5 Mu g-4 Mu g antibody for 400 Mu g-600 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specif |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AKT3AKT110000207208AKT3_HUMANAKT1_HUMANAKT2_HUMAN
|
| Immunogen Region: |
311-480 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 311-480 of human AKT1/AKT2/AKT3 (NP_005154.2). |
| Immunogen Sequence: |
GTPEYLAPEVLEDNDYGRAV DWWGLGVVMYEMMCGRLPFY NQDHEKLFELILMEEIRFPR TLGPEAKSLLSGLLKKDPKQ RLGGGSEDAKEIMQHRFFAG IVWQHVYEKKLSPPFKPQVT SETDTRYFDEEFTAQMITIT PPDQDDSMECVDSERRPHFP QFSYSASGTA |
| Tissue Specificity | Q9Y243 - In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney.P31749 - Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages.P31751 - Widely expressed. Expressed in myoblasts.Q9Y243 - In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney.P31749 - Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages.P31751 - Widely expressed. Expressed in myoblasts. |
| Alternative Antibody Names | Anti-Rac-Gamma Serine/Threonine-Protein Kinase antibodyAnti-Protein Kinase Akt-3 antibodyAnti-Protein Kinase B Gamma antibodyAnti-Pkb Gamma antibodyAnti-Rac-Pk-Gamma antibodyAnti-Stk-2 antibodyAnti-AKT3 antibodyAnti-PKBG antibodyAnti-Rac-Alpha Serine/Threonine-Protein Kinase antibodyAnti-Protein Kinase B antibodyAnti-Pkb antibodyAnti-Protein Kinase B Alpha antibodyAnti-Pkb Alpha antibodyAnti-Proto-Oncogene C-Akt antibodyAnti-Rac-Pk-Alpha antibodyAnti-AKT1 antibodyAnti-PKB antibodyAnti-RAC antibodyAnti-Rac-Beta Serine/Threonine-Protein Kinase antibodyAnti-Protein Kinase Akt-2 antibodyAnti-Protein Kinase B Beta antibodyAnti-Pkb Beta antibodyAnti-Rac Protein Kinase Beta antibodyAnti-Rac-Pk-Beta antibodyAnti-AKT2 antibodyAnti-Rac-Gamma Serine/Threonine-Protein Kinase antibodyAnti-Protein Kinase Akt-3 antibodyAnti-Protein Kinase B Gamma antibodyAnti-Pkb Gamma antibodyAnti-Rac-Pk-Gamma antibodyAnti-Stk-2 antibodyAnti-AKT3 antibodyAnti-PKBG antibodyAnti-Rac-Alpha Serine/Threonine-Protein Kinase antibodyAnti-Protein Kinase B antibodyAnti-Pkb antibodyAnti-Protein Kinase B Alpha antibodyAnti-Pkb Alpha antibodyAnti-Proto-Oncogene C-Akt antibodyAnti-Rac-Pk-Alpha antibodyAnti-AKT1 antibodyAnti-PKB antibodyAnti-RAC antibodyAnti-Rac-Beta Serine/Threonine-Protein Kinase antibodyAnti-Protein Kinase Akt-2 antibodyAnti-Protein Kinase B Beta antibodyAnti-Pkb Beta antibodyAnti-Rac Protein Kinase Beta antibodyAnti-Rac-Pk-Beta antibodyAnti-AKT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
