| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AKT1 AKT3 207 10000 208 AKT1_HUMAN AKT3_HUMAN AKT2_HUMAN |
| Immunogen Region: | 1-123 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-123 of human AKT1/AKT2/AKT3 (NP_005154.2). |
| Immunogen Sequence: | MSDVAIVKEGWLHKRGEYIK TWRPRYFLLKNDGTFIGYKE RPQDVDQREAPLNNFSVAQC QLMKTERPRPNTFIIRCLQW TTVIERTFHVETPEEREEWT TAIQTVADGLKKQEEEEMDF RSG |
| Tissue Specificity | P31749 - Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages. Q9Y243 - In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney. P31751 - Widely expressed. Expressed in myoblasts. P31749 - Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages. Q9Y243 - In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney. P31751 - Widely expressed. Expressed in myoblasts. |
| Alternative Antibody Names | Anti-Rac-Alpha Serine/Threonine-Protein Kinase antibody Anti-Protein Kinase B antibody Anti-Pkb antibody Anti-Protein Kinase B Alpha antibody Anti-Pkb Alpha antibody Anti-Proto-Oncogene C-Akt antibody Anti-Rac-Pk-Alpha antibody Anti-AKT1 antibody Anti-PKB antibody Anti-RAC antibody Anti-Rac-Gamma Serine/Threonine-Protein Kinase antibody Anti-Protein Kinase Akt-3 antibody Anti-Protein Kinase B Gamma antibody Anti-Pkb Gamma antibody Anti-Rac-Pk-Gamma antibody Anti-Stk-2 antibody Anti-AKT3 antibody Anti-PKBG antibody Anti-Rac-Beta Serine/Threonine-Protein Kinase antibody Anti-Protein Kinase Akt-2 antibody Anti-Protein Kinase B Beta antibody Anti-Pkb Beta antibody Anti-Rac Protein Kinase Beta antibody Anti-Rac-Pk-Beta antibody Anti-AKT2 antibody Anti-Rac-Alpha Serine/Threonine-Protein Kinase antibody Anti-Protein Kinase B antibody Anti-Pkb antibody Anti-Protein Kinase B Alpha antibody Anti-Pkb Alpha antibody Anti-Proto-Oncogene C-Akt antibody Anti-Rac-Pk-Alpha antibody Anti-AKT1 antibody Anti-PKB antibody Anti-RAC antibody Anti-Rac-Gamma Serine/Threonine-Protein Kinase antibody Anti-Protein Kinase Akt-3 antibody Anti-Protein Kinase B Gamma antibody Anti-Pkb Gamma antibody Anti-Rac-Pk-Gamma antibody Anti-Stk-2 antibody Anti-AKT3 antibody Anti-PKBG antibody Anti-Rac-Beta Serine/Threonine-Protein Kinase antibody Anti-Protein Kinase Akt-2 antibody Anti-Protein Kinase B Beta antibody Anti-Pkb Beta antibody Anti-Rac Protein Kinase Beta antibody Anti-Rac-Pk-Beta antibody Anti-AKT2 antibody |
Information sourced from Uniprot.org
