| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AKR7A3 |
| Gene ID: | 22977 |
| Uniprot ID: | ARK73_HUMAN |
| Immunogen Region: | 1-331 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human AKR7A3 (NP_036199.2). |
| Immunogen Sequence: | MSRQLSRARPATVLGAMEMG RRMDAPTSAAVTRAFLERGH TEIDTAFVYSEGQSETILGG LGLRLGGSDCRVKIDTKAIP LFGNSLKPDSLRFQLETSLK RLQCPRVDLFYLHMPDHSTP VEETLRACHQLHQEGKFVEL GLSNYAAWEVAEICTLCKSN GWILPTVYQGMYNAITRQVE TELFPCLRHFGLRFYAFNPL AGGLLTGKYKYEDKNGKQPV GRFFGNTWAEMYRNRYWKE |
| Tissue Specificity | Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium. |
| Function | Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. |
| Protein Name | Aflatoxin B1 Aldehyde Reductase Member 3Afb1 Aldehyde Reductase 2Afb1-Ar 2 |
| Database Links | Reactome: R-HSA-5423646 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Aflatoxin B1 Aldehyde Reductase Member 3 antibodyAnti-Afb1 Aldehyde Reductase 2 antibodyAnti-Afb1-Ar 2 antibodyAnti-AKR7A3 antibodyAnti-AFAR2 antibody |
Information sourced from Uniprot.org