| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AKR7A3 (1-331) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AKR7A3 |
| Gene ID: |
22977 |
| Uniprot ID: |
ARK73_HUMAN |
| Immunogen Region: |
1-331 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human AKR7A3 (NP_036199.2). |
| Immunogen Sequence: |
MSRQLSRARPATVLGAMEMG RRMDAPTSAAVTRAFLERGH TEIDTAFVYSEGQSETILGG LGLRLGGSDCRVKIDTKAIP LFGNSLKPDSLRFQLETSLK RLQCPRVDLFYLHMPDHSTP VEETLRACHQLHQEGKFVEL GLSNYAAWEVAEICTLCKSN GWILPTVYQGMYNAITRQVE TELFPCLRHFGLRFYAFNPL AGGLLTGKYKYEDKNGKQPV GRFFGNTWAEMYRNRYWKE |
| Tissue Specificity | Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium. |
| Function | Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. |
| Protein Name | Aflatoxin B1 Aldehyde Reductase Member 3Afb1 Aldehyde Reductase 2Afb1-Ar 2 |
| Database Links | Reactome: R-HSA-5423646 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Aflatoxin B1 Aldehyde Reductase Member 3 antibodyAnti-Afb1 Aldehyde Reductase 2 antibodyAnti-Afb1-Ar 2 antibodyAnti-AKR7A3 antibodyAnti-AFAR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
