Anti-AIF1 antibody (STJ192269)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Allograft inflammatory factor 1 for use in WB, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:5000IF 1:100-300 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AIF1 |
| Gene ID | 199 |
| Uniprot ID | AIF1_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | AIF1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Phosphorylated on serine residues. |
| Function | Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. |
| Protein Name | Allograft Inflammatory Factor 1Aif-1Ionized Calcium-Binding Adapter Molecule 1Protein G1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionRuffle MembranePeripheral Membrane ProteinCytoplasmic SidePhagocytic CupAssociated With The Actin Cytoskeleton At Membrane Ruffles And At Sites Of Phagocytosis |
| Alternative Antibody Names | Anti-Allograft Inflammatory Factor 1 antibodyAnti-Aif-1 antibodyAnti-Ionized Calcium-Binding Adapter Molecule 1 antibodyAnti-Protein G1 antibodyAnti-AIF1 antibodyAnti-G1 antibodyAnti-IBA1 antibody |
Information sourced from Uniprot.org