Immunohistochemical analysis of paraffin-embedded human spleen tissue. 1, primary Antibody was diluted at 1:200 (4ยฐC overnight). 2, Sodium citrate pH 6.0 was used for antigen retrieval (>98ยฐC, 20min). 3, Secondary antibody was diluted at 1:200

Anti-AHSP antibody (1-51 aa) (STJ196177)

⇓ Datasheet ⇓ SDS
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human AHSP at the amino acid range 1-51
STJ196177
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General Information

Short DescriptionRabbit polyclonal anti-Alpha-hemoglobin-stabilizing protein (1-51 aa) for use in IHC and IF in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC/IF
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeIHC-P 1:50-200
IF 1:50-200
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolAHSP
Gene ID51327
Uniprot IDAHSP_HUMAN
ImmunogenSynthesized peptide derived from the human AHSP at the amino acid range 1-51
Immunogen Region1-51 aa
SpecificityThis antibody detects endogenous levels of AHSP at Human/Mouse

Additional Info

Function Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.
Protein Name Alpha-Hemoglobin-Stabilizing Protein
Erythroid Differentiation-Related Factor
Erythroid-Associated Factor
Database Links
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Alpha-Hemoglobin-Stabilizing Protein antibody
Anti-Erythroid Differentiation-Related Factor antibody
Anti-Erythroid-Associated Factor antibody
Anti-AHSP antibody
Anti-EDRF antibody
Anti-ERAF antibody

Information sourced from Uniprot.org

Citations

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