| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Activator of 90 kDa heat shock protein ATPase homolog 1 (161-210 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000-20000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AHSA1 |
| Gene ID: |
10598 |
| Uniprot ID: |
AHSA1_HUMAN |
| Immunogen Region: |
161-210 aa |
| Specificity: |
AHA-1 Polyclonal Antibody detects endogenous levels of AHA-1 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human AHSA1 at the amino acid range 161-210 |
| Post Translational Modifications | Phosphorylation at Tyr-223 enhances binding to chaperone HSP90AA1. |
| Function | Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. |
| Protein Name | Activator Of 90 Kda Heat Shock Protein Atpase Homolog 1Aha1P38 |
| Cellular Localisation | CytoplasmCytosolEndoplasmic ReticulumMay Transiently Interact With The Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Activator Of 90 Kda Heat Shock Protein Atpase Homolog 1 antibodyAnti-Aha1 antibodyAnti-P38 antibodyAnti-AHSA1 antibodyAnti-C14orf3 antibodyAnti-HSPC322 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
