Host: |
Mouse |
Applications: |
ELISA/FC/IF/IHC/RIM |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-Alpha fetoprotein is suitable for use in ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry and RIM research applications. |
Clonality: |
Monoclonal |
Clone ID: |
D10 |
Conjugation: |
Unconjugated |
Isotype: |
IgG1k |
Formulation: |
PBS with 0.02% Sodium Azide. |
Purification: |
Affinity purified from tissue culture. |
Concentration: |
Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
Dilution Range: |
ELISA (solid phase: 0, 1-100 µg/ml; tracer: 0, 001-100 µg/ml for 30 min at RT). Flow cytometry (0, 5-1, 0 µg/million cells in 0, 1 ml). Immunofluorescence (0, 5-1, 0 µg/ml). Immunohistology (1-2 µg/ml for 30 min at RT). RIM (solid phase 0, 6 mg/ml, t |
Storage Instruction: |
Store for up to 1 year at 2-8°C upon receipt. |
Gene Symbol: |
AFP |
Gene ID: |
174 |
Uniprot ID: |
FETA_HUMAN |
Immunogen: |
A BALB/c mouse was immunized with alpha fetoprotein isolated from serum of hepatoma patients. Fusion partner: Sp2/0. |
Tissue Specificity | Plasma. Synthesized by the fetal liver and yolk sac. |
Post Translational Modifications | Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence. Sulfated. |
Function | Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. |
Protein Name | Alpha-FetoproteinAlpha-1-FetoproteinAlpha-Fetoglobulin |
Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Alpha-Fetoprotein antibodyAnti-Alpha-1-Fetoprotein antibodyAnti-Alpha-Fetoglobulin antibodyAnti-AFP antibodyAnti-HPAFP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance