| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-ADRB3 (N-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 45kDa band observed in Human Brain (Cortex) lysates (calculated MW of 43.5kDa according to NP_000016.1). Recommended concentration: 0.03-0.1µg/ml. Primary incubation was 1 hour |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | ADRB3 |
| Gene ID: | 155 |
| Uniprot ID: | ADRB3_HUMAN |
| Immunogen Region: | N-Term |
| Accession Number: | NP_000016.1 |
| Immunogen Sequence: | PHENSSLAPWPD |
| Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. |
| Protein Name | Beta-3 Adrenergic ReceptorBeta-3 AdrenoreceptorBeta-3 Adrenoceptor |
| Database Links | Reactome: R-HSA-390696Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Beta-3 Adrenergic Receptor antibodyAnti-Beta-3 Adrenoreceptor antibodyAnti-Beta-3 Adrenoceptor antibodyAnti-ADRB3 antibodyAnti-ADRB3R antibodyAnti-B3AR antibody |
Information sourced from Uniprot.org