| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADRB3 |
| Gene ID: | 155 |
| Uniprot ID: | ADRB3_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ADRB3 (NP_000016.1). |
| Immunogen Sequence: | MAPWPHENSSLAPWPDLPTL APNTANTSGLPGVPWEAALA GALLALAVLATVGGNLLVIV AIAWTPRLQTMTNVFVTSLA AADLVMGLLVVPPAATLALT |
| Tissue Specificity | Expressed mainly in adipose tissues. |
| Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. |
| Protein Name | Beta-3 Adrenergic ReceptorBeta-3 AdrenoreceptorBeta-3 Adrenoceptor |
| Database Links | Reactome: R-HSA-390696Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Beta-3 Adrenergic Receptor antibodyAnti-Beta-3 Adrenoreceptor antibodyAnti-Beta-3 Adrenoceptor antibodyAnti-ADRB3 antibodyAnti-ADRB3R antibodyAnti-B3AR antibody |
Information sourced from Uniprot.org