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![Anti-ADRB2 nanobody [SAA1015] (STJN000116)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/200729/412911/STJN000116-SDS-PAGE-1__16700.1749232447.jpg?c=1 "Anti-ADRB2 nanobody [SAA1015] (STJN000116)")
Anti-ADRB2 nanobody [SAA1015] (STJN000116)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-Beta-2 Adrenergic Receptor is suitable for use in ELISA research applications. |
| Applications | ELISA |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1015 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | ADRB2 |
| Gene ID | 154 |
| Uniprot ID | ADRB2_HUMAN |
Additional Info
| Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
| Protein Name | Beta-2 Adrenergic ReceptorBeta-2 AdrenoreceptorBeta-2 Adrenoceptor |
| Database Links | Reactome: R-HSA-390696Reactome: R-HSA-418555Reactome: R-HSA-5689880Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEarly EndosomeGolgi ApparatusColocalizes With Vhl At The Cell MembraneActivated Receptors Are Internalized Into Endosomes Prior To Their Degradation In LysosomesActivated Receptors Are Also Detected Within The Golgi Apparatus |
| Alternative Nanobody Names | Anti-Beta-2 Adrenergic Receptor nanobodyAnti-Beta-2 Adrenoreceptor nanobodyAnti-Beta-2 Adrenoceptor nanobodyAnti-ADRB2 nanobodyAnti-ADRB2R nanobodyAnti-B2AR nanobody |
Information sourced from Uniprot.org