Anti-ADRB2 nanobody [SAA1015] (STJN000116)

Anti-ADRB2 nanobody [SAA1015] (STJN000116)

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STJN000116
£195.50 - £1,319.50
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Host: Alpaca
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Beta-2 Adrenergic Receptor is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1015
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: ADRB2
Gene ID: 154
Uniprot ID: ADRB2_HUMAN
Function Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Protein Name Beta-2 Adrenergic Receptor
Beta-2 Adrenoreceptor
Beta-2 Adrenoceptor
Database Links Reactome: R-HSA-390696
Reactome: R-HSA-418555
Reactome: R-HSA-5689880
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Early Endosome
Golgi Apparatus
Colocalizes With Vhl At The Cell Membrane
Activated Receptors Are Internalized Into Endosomes Prior To Their Degradation In Lysosomes
Activated Receptors Are Also Detected Within The Golgi Apparatus
Alternative Nanobody Names Anti-Beta-2 Adrenergic Receptor nanobody
Anti-Beta-2 Adrenoreceptor nanobody
Anti-Beta-2 Adrenoceptor nanobody
Anti-ADRB2 nanobody
Anti-ADRB2R nanobody
Anti-B2AR nanobody

Information sourced from Uniprot.org

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