Anti-ADRB2 antibody (321-370 aa) (STJ91726)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human Adrenergic Receptor beta2 at the amino acid range 321-370
General Information
| Short Description | Rabbit polyclonal anti-Beta-2 adrenergic receptor (321-370 aa) for use in WB, IHC, IF, FC and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/FC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000FC 1:200-1:400ELISA 1:5000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADRB2 |
| Gene ID | 154 |
| Uniprot ID | ADRB2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human Adrenergic Receptor beta2 at the amino acid range 321-370 |
| Immunogen Region | 321-370 aa |
| Specificity | AR-Beta 2 Polyclonal Antibody detects endogenous levels of AR-Beta 2 protein. |
Additional Info
| Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
| Protein Name | Beta-2 Adrenergic ReceptorBeta-2 AdrenoreceptorBeta-2 Adrenoceptor |
| Database Links | Reactome: R-HSA-390696Reactome: R-HSA-418555Reactome: R-HSA-5689880Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEarly EndosomeGolgi ApparatusColocalizes With Vhl At The Cell MembraneActivated Receptors Are Internalized Into Endosomes Prior To Their Degradation In LysosomesActivated Receptors Are Also Detected Within The Golgi Apparatus |
| Alternative Antibody Names | Anti-Beta-2 Adrenergic Receptor antibodyAnti-Beta-2 Adrenoreceptor antibodyAnti-Beta-2 Adrenoceptor antibodyAnti-ADRB2 antibodyAnti-ADRB2R antibodyAnti-B2AR antibody |
Information sourced from Uniprot.org