Host: |
Rabbit |
Applications: |
WB/IHC/IF/FC/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Beta-2 adrenergic receptor (321-370 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000FC 1:200-1:400ELISA 1:5000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ADRB2 |
Gene ID: |
154 |
Uniprot ID: |
ADRB2_HUMAN |
Immunogen Region: |
321-370 aa |
Specificity: |
AR-Beta 2 Polyclonal Antibody detects endogenous levels of AR-Beta 2 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human Adrenergic Receptor beta2 at the amino acid range 321-370 |
Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
Protein Name | Beta-2 Adrenergic ReceptorBeta-2 AdrenoreceptorBeta-2 Adrenoceptor |
Database Links | Reactome: R-HSA-390696Reactome: R-HSA-418555Reactome: R-HSA-5689880Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEarly EndosomeGolgi ApparatusColocalizes With Vhl At The Cell MembraneActivated Receptors Are Internalized Into Endosomes Prior To Their Degradation In LysosomesActivated Receptors Are Also Detected Within The Golgi Apparatus |
Alternative Antibody Names | Anti-Beta-2 Adrenergic Receptor antibodyAnti-Beta-2 Adrenoreceptor antibodyAnti-Beta-2 Adrenoceptor antibodyAnti-ADRB2 antibodyAnti-ADRB2R antibodyAnti-B2AR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance