ADRA1B antibody western blot HeLa PC-3 lysates STJA0037503

Anti-ADRA1B antibody (STJA0037503)

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STJA0037503
£133.50 - £281.50
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Short Description :Rabbit monoclonal anti-ADRA1B for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC-P
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Purified
Dilution Range:WB-1:1000-1:5000
IHC-P-1:200-1:500
Formulation:Liquid in 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:ADRA1B
Gene ID:147
Uniprot ID:ADA1B_HUMAN
Immunogen:Peptide
Function This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
Protein Name Alpha-1b Adrenergic Receptor
Alpha-1b Adrenoreceptor
Alpha-1b Adrenoceptor
Database Links Reactome: R-HSA-390696
Reactome: R-HSA-416476
Reactome: R-HSA-416482
Cellular Localisation Nucleus Membrane
Multi-Pass Membrane Protein
Cell Membrane
Cytoplasm
Membrane
Caveola
Location At The Nuclear Membrane Facilitates Heterooligomerization And Regulates Erk-Mediated Signaling In Cardiac Myocytes
Signaling In Cardiac Myocytes
Colocalizes With Gnaq
Plcb1 As Well As Lap2 At The Nuclear Membrane Of Cardiac Myocytes
Alternative Antibody Names Anti-Alpha-1b Adrenergic Receptor antibody
Anti-Alpha-1b Adrenoreceptor antibody
Anti-Alpha-1b Adrenoceptor antibody
Anti-ADRA1B antibody

Information sourced from Uniprot.org

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