Anti-ADM2 antibody (STJA0004548)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide of human ADM2
General Information
| Short Description | Rabbit polyclonal anti-Protein Adm2 for use in IHC and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.7 mg/mL |
| Purification | Affinity purification |
| Dilution Range | IHC 1:50-1:200 |
| Formulation | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | ADM2 |
| Gene ID | 79924 |
| Uniprot ID | ADM2_HUMAN |
| Immunogen | Synthetic peptide of human ADM2 |
Additional Info
| Tissue Specificity | Expressed in the esophagus, stomach, jejunum, ileum, ileocecum, ascending colon, transverse colon, descending colon and rectum. Expressed in myocardial cells of the heart, renal tubular cells, hypothalamus, and pituitary. |
| Function | Intermedin/ADM2 is a peptide hormone that plays a role as physiological regulator of gastrointestinal and cardiovascular bioactivities mediated by the CALCRL-RAMPs receptor complexes. Activates the cAMP-dependent pathway through interaction with CALCRL-RAMP3 receptor complex. |
| Protein Name | Protein Adm2Intermedin Cleaved Into - Adrenomedullin-2Am2Intermedin-LongImdl - Intermedin-ShortImds |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-419812 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Protein Adm2 antibodyAnti-Intermedin Cleaved Into - Adrenomedullin-2 antibodyAnti-Am2 antibodyAnti-Intermedin-Long antibodyAnti-Imdl - Intermedin-Short antibodyAnti-Imds antibodyAnti-ADM2 antibodyAnti-AM2 antibody |
Information sourced from Uniprot.org