• Western blot analysis of lysate from mouse kidney cells, using ADM Antibody.
  • Immunohistochemical analysis of paraffin-embedded rat-kidney, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded rat-kidney, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
  • Western blot analysis of mouse kidney, mouse lung, mouse heart cells using ADM Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-ADM antibody (101-150 aa) (STJ96567)

SKU:
STJ96567

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Pro-adrenomedullin (101-150 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ADM
Gene ID: 133
Uniprot ID: ADML_HUMAN
Immunogen Region: 101-150 aa
Specificity: ADM Polyclonal Antibody detects endogenous levels of ADM protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human ADM at the amino acid range 101-150
Function AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.
Protein Name Pro-Adrenomedullin Cleaved Into - Adrenomedullin
Am - Proadrenomedullin N-20 Terminal Peptide
Proam N-Terminal 20 Peptide
Pamp
Proam-N20
Database Links Reactome: R-HSA-418555
Reactome: R-HSA-419812
Cellular Localisation Secreted
Alternative Antibody Names Anti-Pro-Adrenomedullin Cleaved Into - Adrenomedullin antibody
Anti-Am - Proadrenomedullin N-20 Terminal Peptide antibody
Anti-Proam N-Terminal 20 Peptide antibody
Anti-Pamp antibody
Anti-Proam-N20 antibody
Anti-ADM antibody
Anti-AM antibody

Information sourced from Uniprot.org

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