Anti-ADH7 antibody (1-386) (STJ110181)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ADH7 (1-386) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADH7 |
| Gene ID | 131 |
| Uniprot ID | ADH7_HUMAN |
| Immunogen Region | 1-386 |
| Immunogen Sequence | MFAEIQIQDKDRMGTAGKVI KCKAAVLWEQKQPFSIEEIE VAPPKTKEVRIKILATGICR TDDHVIKGTMVSKFPVIVGH EATGIVESIGEGVTTVKPGD KVIPLFLPQCRECNACRNPD GNLCIRSDITGRGVLADGTT RFTCKGKPVHHFMNTSTFTE YTVVDESSVAKIDDAAPPEK VCLIGCGFSTGYGAAVKTGK VKPGSTCVVFGLGGVGLSVI MGCKSAGASRIIGIDLNKD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-386 of human ADH7 (NP_000664.2). |
Additional Info
| Tissue Specificity | Preferentially expressed in stomach. |
| Function | Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, and omega-hydroxy fatty acids and their derivatives. Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis-retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid. In vitro can also catalyze the NADH-dependent reduction of all-trans-retinal and aldehydes and their derivatives. Reduces preferentially all trans-retinal, all-trans-4-oxoretinal and hexanal. Catalyzes in the oxidative direction with higher efficiency. Therefore may participate in retinoid metabolism, fatty acid omega-oxidation, and elimination of cytotoxic aldehydes produced by lipid peroxidation. |
| Protein Name | All-Trans-Retinol Dehydrogenase Nad(+ Adh7Alcohol Dehydrogenase Class 4 Mu/Sigma ChainAlcohol Dehydrogenase Class Iv Mu/Sigma ChainGastric Alcohol DehydrogenaseOmega-Hydroxydecanoate Dehydrogenase Adh7Retinol Dehydrogenase |
| Database Links | Reactome: R-HSA-71384 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-All-Trans-Retinol Dehydrogenase Nad(+ Adh7 antibodyAnti-Alcohol Dehydrogenase Class 4 Mu/Sigma Chain antibodyAnti-Alcohol Dehydrogenase Class Iv Mu/Sigma Chain antibodyAnti-Gastric Alcohol Dehydrogenase antibodyAnti-Omega-Hydroxydecanoate Dehydrogenase Adh7 antibodyAnti-Retinol Dehydrogenase antibodyAnti-ADH7 antibody |
Information sourced from Uniprot.org