Anti-ADGRL1 antibody (561-610 aa) (STJ93906)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human LPHN1 at the amino acid range 561-610
General Information
| Short Description | Rabbit polyclonal anti-Adhesion G protein-coupled receptor L1 (561-610 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADGRL1 |
| Gene ID | 22859 |
| Uniprot ID | AGRL1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human LPHN1 at the amino acid range 561-610 |
| Immunogen Region | 561-610 aa |
| Specificity | Latrophilin-1 Polyclonal Antibody detects endogenous levels of Latrophilin-1 protein. |
Additional Info
| Function | Calcium-independent receptor of high affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis. |
| Protein Name | Adhesion G Protein-Coupled Receptor L1Calcium-Independent Alpha-Latrotoxin Receptor 1Cirl-1Latrophilin-1Lectomedin-2 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionAxonGrowth ConeSynapsePresynaptic Cell MembraneSynaptosomeColocalizes With Tenm2 On The Cell SurfaceAcross Intercellular Junctions And On Nerve Terminals Near Synaptic Clefts |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor L1 antibodyAnti-Calcium-Independent Alpha-Latrotoxin Receptor 1 antibodyAnti-Cirl-1 antibodyAnti-Latrophilin-1 antibodyAnti-Lectomedin-2 antibodyAnti-ADGRL1 antibodyAnti-KIAA0821 antibodyAnti-LEC2 antibodyAnti-LPHN1 antibody |
Information sourced from Uniprot.org