| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | ADGRG3 |
| Gene ID: | 222487 |
| Uniprot ID: | AGRG3_HUMAN |
| Immunogen Region: | 21-270 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-270 of human ADGRG3 (NP_740746.4). |
| Immunogen Sequence: | QEKPTEGPRNTCLGSNNMYD IFNLNDKALCFTKCRQSGSD SCNVENLQRYWLNYEAHLMK EGLTQKVNTPFLKALVQNLS TNTAEDFYFSLEPSQVPRQV MKDEDKPPDRVRLPKSLFRS LPGNRSVVRLAVTILDIGPG TLFKGPRLGLGDGSGVLNNR LVGLSVGQMHVTKLAEPLEI VFSHQRPPPNMTLTCVFWDV TKGTTGDWSSEGCSTEVRPE GTVCCCDHLTFFALLLRPT |
| Tissue Specificity | Expressed in cultured primary dermal lymphatic endothelial cells. |
| Post Translational Modifications | Autoproteolytically processed at the GPS region of the GAIN-B domain.this cleavage modulates receptor activity. |
| Function | Orphan receptor that regulates migration of lymphatic endothelial cells in vitro via the small GTPases RhoA and CDC42. Regulates B-cell development. Seems to signal through G-alpha(q)-proteins. |
| Protein Name | Adhesion G Protein-Coupled Receptor G3G-Protein Coupled Receptor 97G-Protein Coupled Receptor Pgr26 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor G3 antibodyAnti-G-Protein Coupled Receptor 97 antibodyAnti-G-Protein Coupled Receptor Pgr26 antibodyAnti-ADGRG3 antibodyAnti-GPR97 antibodyAnti-PGR26 antibody |
Information sourced from Uniprot.org