| Short Description : | Rabbit polyclonal anti-Adhesion G protein-coupled receptor E3 (603-652 aa) for use in WB, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:10000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADGRE3 |
| Gene ID: | 84658 |
| Uniprot ID: | AGRE3_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human EMR3 at the amino acid range 603-652 |
| Immunogen Region: | 603-652 aa |
| Specificity: | EMR3 Polyclonal Antibody detects endogenous levels of EMR3 protein. |
| Post Translational Modifications | Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. |
| Function | Orphan receptor that may play a role myeloid-myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of monocytes-derived macrophages and activated neutrophils. |
| Protein Name | Adhesion G Protein-Coupled Receptor E3Egf-Like Module Receptor 3Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 3 |
| Database Links | Reactome: R-HSA-373080Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinIsoform 3: Secreted |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor E3 antibodyAnti-Egf-Like Module Receptor 3 antibodyAnti-Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 3 antibodyAnti-ADGRE3 antibodyAnti-EMR3 antibodyAnti-UNQ683 antibodyAnti-PRO1562 antibody |
Information sourced from Uniprot.org
