| Host: |
Rabbit |
| Applications: |
ELISA/IP/WB |
| Reactivity: |
Gorilla/Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Adenylate Cyclase 10 (200-250) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.55-0.75 µg/µl |
| Dilution Range: |
WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:150 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Adcy10 |
| Gene ID: |
271639 |
| Uniprot ID: |
ADCYA_MOUSE |
| Immunogen Region: |
200-250 |
| Immunogen: |
Synthetic peptide taken within amino acid region 200-250 on mouse Adenylate Cyclase type 10 protein. |
| Tissue Specificity | Expressed in testis. |
| Function | Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation. |
| Protein Name | Adenylate Cyclase Type 10Germ Cell Soluble Adenylyl CyclaseSacTesticular Soluble Adenylyl Cyclase |
| Database Links | Reactome: R-MMU-5610787 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonPerinuclear RegionNucleusCell ProjectionCiliumMitochondrionDistributed To Subcellular Compartments Containing Camp TargetsFound As A Plasma Membrane-Associated ProteinProtein Concentrated In The Perinuclear Region And Protein Colocalized With Actin Or Tubulin |
| Alternative Antibody Names | Anti-Adenylate Cyclase Type 10 antibodyAnti-Germ Cell Soluble Adenylyl Cyclase antibodyAnti-Sac antibodyAnti-Testicular Soluble Adenylyl Cyclase antibodyAnti-Adcy10 antibodyAnti-Sac antibodyAnti-Sacy antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
