Anti-ADCYAP1R1 antibody [SAA0130] (STJA0027404)
SPECIFICATIONS
ClonalityMonoclonal
HostHuman
ConjugationUnconjugated
IsotypeIgG1k
General Information
| Short Description | Human monoclonal Pituitary Adenylate Cyclase-Activating Polypeptide Type I Receptor antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Human |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0130 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1.45 mg/ml |
| Purification | Protein A/G purified from cell culture supernatant. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | ADCYAP1R1 |
| Gene ID | 117 |
| Uniprot ID | PACR_HUMAN |
Additional Info
| Function | G protein-coupled receptor activated by the neuropeptide pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP). Binds both PACAP27 and PACAP38 bioactive peptides. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. |
| Protein Name | Pituitary Adenylate Cyclase-Activating Polypeptide Type I ReceptorPac1 ReceptorPac1rPacap Type I ReceptorPacap-R-1Pacap-R1 |
| Database Links | Reactome: R-HSA-187024Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Pituitary Adenylate Cyclase-Activating Polypeptide Type I Receptor antibodyAnti-Pac1 Receptor antibodyAnti-Pac1r antibodyAnti-Pacap Type I Receptor antibodyAnti-Pacap-R-1 antibodyAnti-Pacap-R1 antibodyAnti-ADCYAP1R1 antibody |
Information sourced from Uniprot.org